2002. Riccardo Giacconi (1931-), The Johns Hopkins University, won Nobel Prize in Physics.
2003. Peter Agre (1949-), The Johns Hopkins University, won Nobel Prize in Chemistry.
2003, Oct. 1-2006, Jan. 3. Gordon R. England of Baltimore served as U.S. Secretary of the Navy.
2004, March 2. Electronic voting system used during primary elections at polling places and for absentee ballots in all counties and Baltimore City.
2007, Jan. 4. Baltimore native, Nancy D'Alesandro Pelosi sworn in as first women Speaker of U.S. House of Representatives.
2009. Carol W. Greider (1961-), The Johns Hopkins University, won Nobel Prize in Medicine.
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